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Oleic acid differentially affects de novo lipogenesis in adipocytes and hepatocytes

Lipogenesis is a vital but often dysregulated metabolic pathway. We report super-resolution multiplexed vibrational imaging of lipogenesis rates and pathways using isotopically labelled oleic acid and glucose as probes in live adipocytes and hepatocytes. These findings suggest oleic acid inhibits de...

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Detalles Bibliográficos
Autores principales: Castillo, Hannah B., Shuster, Sydney O., Tarekegn, Lydia H., Davis, Caitlin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592964/
https://www.ncbi.nlm.nih.gov/pubmed/37873279
http://dx.doi.org/10.1101/2023.10.04.560581