Dissecting telomerase RNA structural heterogeneity in living human cells with DMS-MaPseq

Telomerase is a specialized reverse transcriptase that uses an intrinsic RNA subunit as the template for telomeric DNA synthesis. Biogenesis of human telomerase requires its RNA subunit (hTR) to fold into a multi-domain architecture that includes the template-containing pseudoknot (t/PK) and the thr...

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Detalles Bibliográficos
Autores principales: Forino, Nicholas M., Woo, Jia Zheng, Zaug, Arthur J., Jimenez, Arcelia Gonzalez, Cech, Thomas R., Rouskin, Silvi, Stone, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592977/
https://www.ncbi.nlm.nih.gov/pubmed/37873413
http://dx.doi.org/10.1101/2023.10.04.560962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592977/
https://www.ncbi.nlm.nih.gov/pubmed/37873413
http://dx.doi.org/10.1101/2023.10.04.560962

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