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CED-5/CED-12 (DOCK/ELMO) can promote and inhibit F-actin formation via distinct motifs that target different GTPases

Coordinated activation and inhibition of F-actin supports the movements of morphogenesis. Understanding the proteins that regulate F-actin is important, since these proteins are mis-regulated in diseases like cancer. Our studies of C. elegans embryonic epidermal morphogenesis identified the GTPase C...

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Detalles Bibliográficos
Autores principales: Venkatachalam, Thejasvi, Mannimala, Sushma, Soto, Martha C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592980/
https://www.ncbi.nlm.nih.gov/pubmed/37873140
http://dx.doi.org/10.1101/2023.10.04.560868