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Discovery of Ancestry-specific Variants Associated with Clopidogrel Response among Caribbean Hispanics

BACKGROUND. High on-treatment platelet reactivity (HTPR) with clopidogrel is predictive of ischemic events in adults with coronary artery disease. Despite strong data suggesting HTPR varies with ethnicity, including clinical and genetic variables, no genome-wide association study (GWAS) of clopidogr...

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Detalles Bibliográficos
Autores principales: Yang, Guang, González, Pablo, Moneró, Mariangeli, Carrasquillo, Kelvin, Renta, Jessicca Y., Hernandez-Suarez, Dagmar F., Botton, Mariana R., Melin, Kyle, Scott, Stuart A., Ruaño, Gualberto, Roche-Lima, Abiel, Alarcon, Cristina, Ritchie, Marylyn D., Perera, Minoli A., Duconge, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593031/
https://www.ncbi.nlm.nih.gov/pubmed/37873439
http://dx.doi.org/10.1101/2023.09.29.23296372