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A clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease

Chronic kidney disease (CKD) is a complex disorder that causes a gradual loss of kidney function, affecting approximately 9.1% of the world’s population. Here, we use a soft-clustering algorithm to deconstruct its genetic heterogeneity. First, we selected 322 CKD-associated independent genetic varia...

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Detalles Bibliográficos
Autores principales: Eoli, A., Ibing, S., Schurmann, C., Nadkarni, G.N., Heyne, H.O., Böttinger, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593036/
https://www.ncbi.nlm.nih.gov/pubmed/37873472
http://dx.doi.org/10.1101/2023.10.12.23296926