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De Novo Biosynthesis of Vindoline and Catharanthine in Saccharomyces cerevisiae
Vinblastine has been used clinically as one of the most potent therapeutics for the treatment of several types of cancer. However, the traditional plant extraction method suffers from unreliable supply, low abundance, and extremely high cost. Here, we use synthetic biology approach to engineer Sacch...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAAS
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593122/ https://www.ncbi.nlm.nih.gov/pubmed/37905202 http://dx.doi.org/10.34133/bdr.0002 |