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De Novo Biosynthesis of Vindoline and Catharanthine in Saccharomyces cerevisiae

Vinblastine has been used clinically as one of the most potent therapeutics for the treatment of several types of cancer. However, the traditional plant extraction method suffers from unreliable supply, low abundance, and extremely high cost. Here, we use synthetic biology approach to engineer Sacch...

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Detalles Bibliográficos
Autores principales:	Gao, Di, Liu, Tengfei, Gao, Jucan, Xu, Junhao, Gou, Yuanwei, Pan, Yingjia, Li, Dongfang, Ye, Cuifang, Pan, Ronghui, Huang, Lei, Xu, Zhinan, Lian, Jiazhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAAS 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593122/ https://www.ncbi.nlm.nih.gov/pubmed/37905202 http://dx.doi.org/10.34133/bdr.0002

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