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Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis

Chicken lung is an important target organ of avian influenza virus (AIV) infection, and different pathogenic virus strains lead to opposite prognosis. Using a single-cell RNA sequencing (scRNA-seq) assay, we systematically and sequentially analyzed the transcriptome of 16 cell types (19 clusters) in...

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Detalles Bibliográficos
Autores principales: Dai, Manman, Zhu, Sufang, An, Zhihao, You, Bowen, Li, Ziwei, Yao, Yongxiu, Nair, Venugopal, Liao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593216/
https://www.ncbi.nlm.nih.gov/pubmed/37819993
http://dx.doi.org/10.1371/journal.ppat.1011685