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Phertilizer: Growing a clonal tree from ultra-low coverage single-cell DNA sequencing of tumors

Emerging ultra-low coverage single-cell DNA sequencing (scDNA-seq) technologies have enabled high resolution evolutionary studies of copy number aberrations (CNAs) within tumors. While these sequencing technologies are well suited for identifying CNAs due to the uniformity of sequencing coverage, th...

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Detalles Bibliográficos
Autores principales: Weber, Leah L., Zhang, Chuanyi, Ochoa, Idoia, El-Kebir, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593221/
https://www.ncbi.nlm.nih.gov/pubmed/37819942
http://dx.doi.org/10.1371/journal.pcbi.1011544