Human antibody V(H) domains targeting uPAR as candidate therapeutics for cancers

The high expression of uPAR has been linked to tumor progression, invasion, and metastasis in several types of cancer. Such overexpression of uPAR makes it a potential target for immunotherapies across common cancers such as breast, colorectal, lung, ovarian cancer, and melanoma. In our study, two h...

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Detalles Bibliográficos
Autores principales: Chu, Xiaojie, Li, Wei, Hines, Margaret G., Lyakhov, Ilya, Mellors, John W., Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593477/
https://www.ncbi.nlm.nih.gov/pubmed/37876962
http://dx.doi.org/10.3389/fonc.2023.1194972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593477/
https://www.ncbi.nlm.nih.gov/pubmed/37876962
http://dx.doi.org/10.3389/fonc.2023.1194972

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