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Human antibody V(H) domains targeting uPAR as candidate therapeutics for cancers
The high expression of uPAR has been linked to tumor progression, invasion, and metastasis in several types of cancer. Such overexpression of uPAR makes it a potential target for immunotherapies across common cancers such as breast, colorectal, lung, ovarian cancer, and melanoma. In our study, two h...
Autores principales: | Chu, Xiaojie, Li, Wei, Hines, Margaret G., Lyakhov, Ilya, Mellors, John W., Dimitrov, Dimiter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593477/ https://www.ncbi.nlm.nih.gov/pubmed/37876962 http://dx.doi.org/10.3389/fonc.2023.1194972 |
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