The 5-HT(1A) receptor biased agonists, NLX-204 and NLX-101, display ketamine-like RAAD and anti-TRD activities in rat CMS models

OBJECTIVES: NLX-101 and NLX-204 are highly selective serotonin 5-HT(1A) ‘biased’ agonists, displaying potent and efficacious antidepressant-like activity upon acute administration in models such as the forced swim test. METHODS: we compared the effects of repeated administration of NLX-101, NLX-204...

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Detalles Bibliográficos
Autores principales: Papp, Mariusz, Gruca, Piotr, Lason, Magdalena, Litwa, Ewa, Newman-Tancredi, Adrian, Depoortère, Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593613/
https://www.ncbi.nlm.nih.gov/pubmed/37310446
http://dx.doi.org/10.1007/s00213-023-06389-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593613/
https://www.ncbi.nlm.nih.gov/pubmed/37310446
http://dx.doi.org/10.1007/s00213-023-06389-5

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