Cargando…
The 5-HT(1A) receptor biased agonists, NLX-204 and NLX-101, display ketamine-like RAAD and anti-TRD activities in rat CMS models
OBJECTIVES: NLX-101 and NLX-204 are highly selective serotonin 5-HT(1A) ‘biased’ agonists, displaying potent and efficacious antidepressant-like activity upon acute administration in models such as the forced swim test. METHODS: we compared the effects of repeated administration of NLX-101, NLX-204...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593613/ https://www.ncbi.nlm.nih.gov/pubmed/37310446 http://dx.doi.org/10.1007/s00213-023-06389-5 |