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SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions
Immunoglobulin (Ig) A functions as monomeric IgA in the serum and Secretory (S) IgA in mucosal secretions. Host IgA Fc receptors (FcαRs), including human FcαR1/CD89, mediate IgA effector functions; however, human pathogen Streptococcus pyogenes has evolved surface-protein virulence factors, includin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593759/ https://www.ncbi.nlm.nih.gov/pubmed/37872175 http://dx.doi.org/10.1038/s41467-023-42469-y |