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GWAS for the composite traits of hematuria and albuminuria

Our GWAS of hematuria in the UK Biobank identified 6 loci, some of which overlap with loci for albuminuria suggesting pleiotropy. Since clinical syndromes are often defined by combinations of traits, generating a combined phenotype can improve power to detect loci influencing multiple characteristic...

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Detalles Bibliográficos
Autores principales: Gagliano Taliun, Sarah A., Dinsmore, Ian R., Mirshahi, Tooraj, Chang, Alexander R., Paterson, Andrew D., Barua, Moumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593773/
https://www.ncbi.nlm.nih.gov/pubmed/37872228
http://dx.doi.org/10.1038/s41598-023-45102-6