Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction

The molecular mechanisms connecting cellular metabolism with differentiation remain poorly understood. Here, we find that metabolic signals contribute to stem cell differentiation and germline homeostasis during Drosophila melanogaster spermatogenesis. We discovered that external citrate, originatin...

Descripción completa

Detalles Bibliográficos
Autores principales: François, Charlotte M., Pihl, Thomas, Dunoyer de Segonzac, Marion, Hérault, Chloé, Hudry, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593830/
https://www.ncbi.nlm.nih.gov/pubmed/37872135
http://dx.doi.org/10.1038/s41467-023-42496-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593830/
https://www.ncbi.nlm.nih.gov/pubmed/37872135
http://dx.doi.org/10.1038/s41467-023-42496-9

Ejemplares similares