The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer

Colorectal cancer (CRC) patients with liver metastases usually obtain less benefit from immunotherapy, and the underlying mechanisms remain understudied. Here, we identify that fibrinogen-like protein 1 (FGL1), secreted from cancer cells and hepatocytes, facilitates the progression of CRC in an intr...

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Detalles Bibliográficos
Autores principales: Li, Jia-Jun, Wang, Jin-Hong, Tian, Tian, Liu, Jia, Zheng, Yong-Qiang, Mo, Hai-Yu, Sheng, Hui, Chen, Yan-Xing, Wu, Qi-Nian, Han, Yi, Liao, Kun, Pan, Yi-Qian, Zeng, Zhao-Lei, Liu, Ze-Xian, Yang, Wei, Xu, Rui-Hua, Ju, Huai-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593839/
https://www.ncbi.nlm.nih.gov/pubmed/37872170
http://dx.doi.org/10.1038/s41467-023-42332-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593839/
https://www.ncbi.nlm.nih.gov/pubmed/37872170
http://dx.doi.org/10.1038/s41467-023-42332-0

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