Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons

BACKGROUND: A salient effect of addictive drugs is to hijack the dopamine reward system, an evolutionarily conserved driver of goal-directed behavior and learning. Reduced dopamine type 2 receptor availability in the striatum is an important pathophysiological mechanism for addiction that is both co...

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Detalles Bibliográficos
Autores principales: Guerri, Lucia, Dobbs, Lauren K., da Silva e Silva, Daniel A., Meyers, Allen, Ge, Aaron, Lecaj, Lea, Djakuduel, Caroline, Islek, Damien, Hipolito, Dionisio, Martinez, Abdiel Badillo, Shen, Pei-Hong, Marietta, Cheryl A., Garamszegi, Susanna P., Capobianco, Enrico, Jiang, Zhijie, Schwandt, Melanie, Mash, Deborah C., Alvarez, Veronica A., Goldman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593893/
https://www.ncbi.nlm.nih.gov/pubmed/37881572
http://dx.doi.org/10.1016/j.bpsgos.2022.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593893/
https://www.ncbi.nlm.nih.gov/pubmed/37881572
http://dx.doi.org/10.1016/j.bpsgos.2022.08.010

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