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Transcriptional Profile of Exercise-Induced Protection Against Relapse to Cocaine Seeking in a Rat Model

BACKGROUND: Exercise has shown promise as a treatment for cocaine use disorder; however, the mechanism underlying its efficacy has remained elusive. METHODS: We used a rat model of relapse (cue-induced reinstatement) and exercise (wheel running, 2 hours/day) coupled with RNA sequencing to establish...

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Detalles Bibliográficos
Autores principales: Towers, Eleanor Blair, Shapiro, Daniel A., Abel, Jean M., Bakhti-Suroosh, Anousheh, Kupkova, Kristyna, Auble, David T., Grant, Patrick A., Lynch, Wendy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593899/
https://www.ncbi.nlm.nih.gov/pubmed/37881559
http://dx.doi.org/10.1016/j.bpsgos.2023.01.007