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UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence
Senescence has two roles in oncology: it is known as a potent tumor-suppressive mechanism, which also supports tissue regeneration and repair, it is also known to contribute to reduced patient resilience, which might lead to cancer recurrence and resistance after therapy. Senescence can be activated...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593929/ https://www.ncbi.nlm.nih.gov/pubmed/37872164 http://dx.doi.org/10.1038/s41467-023-42494-x |