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UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence

Senescence has two roles in oncology: it is known as a potent tumor-suppressive mechanism, which also supports tissue regeneration and repair, it is also known to contribute to reduced patient resilience, which might lead to cancer recurrence and resistance after therapy. Senescence can be activated...

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Detalles Bibliográficos
Autores principales: De Magis, Alessio, Limmer, Michaela, Mudiyam, Venkat, Monchaud, David, Juranek, Stefan, Paeschke, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593929/
https://www.ncbi.nlm.nih.gov/pubmed/37872164
http://dx.doi.org/10.1038/s41467-023-42494-x