Pathway-Based Polygenic Risk Scores for Schizophrenia and Associations With Reported Psychotic-like Experiences and Neuroimaging Phenotypes in the UK Biobank

BACKGROUND: Schizophrenia is a heritable psychiatric disorder with a polygenic architecture. Genome-wide association studies have reported that an increasing number of risk-associated variants and polygenic risk scores (PRSs) explain 17% of the variance in the disorder. Substantial heterogeneity exi...

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Detalles Bibliográficos
Autores principales: Barbu, Miruna C., Viejo-Romero, Maria, Thng, Gladi, Adams, Mark J., Marwick, Katie, Grant, Seth G.N., McIntosh, Andrew M., Lawrie, Stephen M., Whalley, Heather C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593950/
https://www.ncbi.nlm.nih.gov/pubmed/37881537
http://dx.doi.org/10.1016/j.bpsgos.2023.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593950/
https://www.ncbi.nlm.nih.gov/pubmed/37881537
http://dx.doi.org/10.1016/j.bpsgos.2023.03.004

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