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Single-Nucleus Transcriptional Profiling of GAD2-Positive Neurons From Mouse Lateral Habenula Reveals Distinct Expression of Neurotransmission- and Depression-Related Genes

BACKGROUND: Glutamatergic projection neurons of the lateral habenula (LHb) drive behavioral state modulation by regulating the activity of midbrain monoaminergic neurons. Identifying circuit mechanisms that modulate LHb output is of interest for understanding control of motivated behaviors. METHODS:...

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Detalles Bibliográficos
Autores principales: Green, Matthew V., Gallegos, David A., Boua, Jane-Valeriane, Bartelt, Luke C., Narayanan, Arthy, West, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593960/
https://www.ncbi.nlm.nih.gov/pubmed/37881543
http://dx.doi.org/10.1016/j.bpsgos.2023.04.004