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Mutual-information based optimal experimental design for hyperpolarized [Formula: see text] C-pyruvate MRI

A key parameter of interest recovered from hyperpolarized (HP) MRI measurements is the apparent pyruvate-to-lactate exchange rate, [Formula: see text] , for measuring tumor metabolism. This manuscript presents an information-theory-based optimal experimental design approach that minimizes the uncert...

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Detalles Bibliográficos
Autores principales: Jha, Prashant K., Walker, Christopher, Mitchell, Drew, Oden, J. Tinsley, Schellingerhout, Dawid, Bankson, James A., Fuentes, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593962/
https://www.ncbi.nlm.nih.gov/pubmed/37872226
http://dx.doi.org/10.1038/s41598-023-44958-y