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Mutual-information based optimal experimental design for hyperpolarized [Formula: see text] C-pyruvate MRI
A key parameter of interest recovered from hyperpolarized (HP) MRI measurements is the apparent pyruvate-to-lactate exchange rate, [Formula: see text] , for measuring tumor metabolism. This manuscript presents an information-theory-based optimal experimental design approach that minimizes the uncert...
Autores principales: | Jha, Prashant K., Walker, Christopher, Mitchell, Drew, Oden, J. Tinsley, Schellingerhout, Dawid, Bankson, James A., Fuentes, David T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593962/ https://www.ncbi.nlm.nih.gov/pubmed/37872226 http://dx.doi.org/10.1038/s41598-023-44958-y |
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