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Methylation of ESR1 promoter induced by SNAI2–DNMT3B complex promotes epithelial–mesenchymal transition and correlates with poor prognosis in ERα‐positive breast cancers

Estrogen receptor α (ERα) serves as an essential therapeutic predictor for breast cancer (BC) patients and is regulated by epigenetic modification. Abnormal methylation of cytosine phosphoric acid guanine islands in the estrogen receptor 1 (ESR1) gene promoter could silence or decrease ERα expressio...

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Detalles Bibliográficos
Autores principales: Li, Ji‐Wei, Deng, Qiu‐Min, Zhu, Jian‐Ling, Min, Wei, Hu, Xiao‐Yi, Yu Chen, Hong‐, Luo, Zhong, Lin, Lin‐Ling, Wei, Xiao‐Long, Zhang, Yong‐Qu, Lou, Kang‐Liang, Gao, Yi‐Yang, Zhang, Guo‐Jun, Bai, Jing‐Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594044/
https://www.ncbi.nlm.nih.gov/pubmed/37881785
http://dx.doi.org/10.1002/mco2.403