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Methylation of ESR1 promoter induced by SNAI2–DNMT3B complex promotes epithelial–mesenchymal transition and correlates with poor prognosis in ERα‐positive breast cancers
Estrogen receptor α (ERα) serves as an essential therapeutic predictor for breast cancer (BC) patients and is regulated by epigenetic modification. Abnormal methylation of cytosine phosphoric acid guanine islands in the estrogen receptor 1 (ESR1) gene promoter could silence or decrease ERα expressio...
Autores principales: | Li, Ji‐Wei, Deng, Qiu‐Min, Zhu, Jian‐Ling, Min, Wei, Hu, Xiao‐Yi, Yu Chen, Hong‐, Luo, Zhong, Lin, Lin‐Ling, Wei, Xiao‐Long, Zhang, Yong‐Qu, Lou, Kang‐Liang, Gao, Yi‐Yang, Zhang, Guo‐Jun, Bai, Jing‐Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594044/ https://www.ncbi.nlm.nih.gov/pubmed/37881785 http://dx.doi.org/10.1002/mco2.403 |
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