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Modulating β-catenin/BCL9 interaction with cell-membrane-camouflaged carnosic acid to inhibit Wnt pathway and enhance tumor immune response

INTRODUCTION: Lung adenocarcinoma (LUAD) therapies are plagued by insufficient immune infiltration and suboptimal immune responses in patients, which are closely associated with the hyperactive Wnt/β-catenin pathway. Suppressing this signaling holds considerable promise as a potential tumor therapy...

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Detalles Bibliográficos
Autores principales: Gao, Ruqing, Zheng, Xiaoqiang, Jiang, Aimin, He, Wangxiao, Liu, Tianya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594212/
https://www.ncbi.nlm.nih.gov/pubmed/37881428
http://dx.doi.org/10.3389/fimmu.2023.1274223