Elucidating Novel Targets for Ovarian Cancer Antibody–Drug Conjugate Development: Integrating In Silico Prediction and Surface Plasmon Resonance to Identify Targets with Enhanced Antibody Internalization Capacity

Antibody–drug conjugates (ADCs) constitute a rapidly expanding category of biopharmaceuticals that are reshaping the landscape of targeted chemotherapy. The meticulous process of selecting therapeutic targets, aided by specific monoclonal antibodies’ high specificity for binding to designated antige...

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Detalles Bibliográficos
Autores principales: Onyido, Emenike Kenechi, James, David, Garcia-Parra, Jezabel, Sinfield, John, Moberg, Anna, Coombes, Zoe, Worthington, Jenny, Williams, Nicole, Francis, Lewis Webb, Conlan, Robert Steven, Gonzalez, Deyarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594448/
https://www.ncbi.nlm.nih.gov/pubmed/37873862
http://dx.doi.org/10.3390/antib12040065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594448/
https://www.ncbi.nlm.nih.gov/pubmed/37873862
http://dx.doi.org/10.3390/antib12040065

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