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Targeting Ribonucleases with Small Molecules and Bifunctional Molecules

[Image: see text] Ribonucleases (RNases) cleave and process RNAs, thereby regulating the biogenesis, metabolism, and degradation of coding and noncoding RNAs. Thus, small molecules targeting RNases have the potential to perturb RNA biology, and RNases have been studied as therapeutic targets of anti...

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Detalles Bibliográficos
Autores principales: Borgelt, Lydia, Wu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594538/
https://www.ncbi.nlm.nih.gov/pubmed/37382390
http://dx.doi.org/10.1021/acschembio.3c00191