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Targeting Ribonucleases with Small Molecules and Bifunctional Molecules
[Image: see text] Ribonucleases (RNases) cleave and process RNAs, thereby regulating the biogenesis, metabolism, and degradation of coding and noncoding RNAs. Thus, small molecules targeting RNases have the potential to perturb RNA biology, and RNases have been studied as therapeutic targets of anti...
Autores principales: | Borgelt, Lydia, Wu, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594538/ https://www.ncbi.nlm.nih.gov/pubmed/37382390 http://dx.doi.org/10.1021/acschembio.3c00191 |
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