Direct Nanopore Sequencing for the 17 RNA Modification Types in 36 Locations in the E. coli Ribosome Enables Monitoring of Stress-Dependent Changes

[Image: see text] The bacterium Escherichia coli possesses 16S and 23S rRNA strands that have 36 chemical modification sites with 17 different structures. Nanopore direct RNA sequencing using a protein nanopore sensor and helicase brake, which is also a sensor, was applied to the rRNAs. Nanopore cur...

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Detalles Bibliográficos
Autores principales: Fleming, Aaron M., Bommisetti, Praneeth, Xiao, Songjun, Bandarian, Vahe, Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594579/
https://www.ncbi.nlm.nih.gov/pubmed/37345867
http://dx.doi.org/10.1021/acschembio.3c00166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594579/
https://www.ncbi.nlm.nih.gov/pubmed/37345867
http://dx.doi.org/10.1021/acschembio.3c00166

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