Cargando…

Practical Synthesis of N-Formylmethionylated Peptidyl-tRNA Mimics

[Image: see text] Hydrolysis-resistant RNA-peptide conjugates that mimic peptidyl-tRNAs are frequently needed for structural and functional studies of protein synthesis in the ribosome. Such conjugates are accessible by chemical solid-phase synthesis, allowing for the utmost flexibility of both the...

Descripción completa

Detalles Bibliográficos
Autores principales: Thaler, Julia, Syroegin, Egor A., Breuker, Kathrin, Polikanov, Yury S., Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594587/
https://www.ncbi.nlm.nih.gov/pubmed/37433044
http://dx.doi.org/10.1021/acschembio.3c00237