N-Sulfenylation of β-Lactams: Radical Reaction of N-Bromo-azetidinones by TEMPO Catalysis

[Image: see text] Azetidinones with a sulfenyl group on the β-lactam nitrogen atom show interesting biological activities as antimicrobial agents and enzyme inhibitors. We report in the present study a versatile synthesis of N-sulfenylated azetidinones starting from the corresponding N-bromo derivat...

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Detalles Bibliográficos
Autores principales: Giraldi, Valentina, Giunchino, Francesco, Casacchia, Maria Edith, Cantelli, Andrea, Lucarini, Marco, Giacomini, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594653/
https://www.ncbi.nlm.nih.gov/pubmed/37769169
http://dx.doi.org/10.1021/acs.joc.3c01759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594653/
https://www.ncbi.nlm.nih.gov/pubmed/37769169
http://dx.doi.org/10.1021/acs.joc.3c01759

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