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Genome-wide analyses identify NEAT1 as genetic modifier of age at onset of amyotrophic lateral sclerosis

BACKGROUND: Patients with amyotrophic lateral sclerosis (ALS) demonstrate great heterogeneity in the age at onset (AAO), which is closely related to the course of disease. However, most genetic studies focused on the risk of ALS, while the genetic background underlying AAO of ALS is still unknown. M...

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Detalles Bibliográficos
Autores principales: Li, Chunyu, Wei, Qianqian, Hou, Yanbing, Lin, Junyu, Ou, Ruwei, Zhang, Lingyu, Jiang, Qirui, Xiao, Yi, Liu, Kuncheng, Chen, Xueping, Yang, TianMi, Song, Wei, Zhao, Bi, Wu, Ying, Shang, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594666/
https://www.ncbi.nlm.nih.gov/pubmed/37872557
http://dx.doi.org/10.1186/s13024-023-00669-6