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Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity
The brain is a highly metabolically active organ requiring a large amount of glucose. Methylglyoxal (MGO), a by-product of glucose metabolism, is known to be involved in microvascular dysfunction and is associated with reduced cognitive function. Maintenance of the blood-brain barrier (BBB) is essen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594715/ https://www.ncbi.nlm.nih.gov/pubmed/37875994 http://dx.doi.org/10.1186/s12987-023-00477-6 |