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Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity

The brain is a highly metabolically active organ requiring a large amount of glucose. Methylglyoxal (MGO), a by-product of glucose metabolism, is known to be involved in microvascular dysfunction and is associated with reduced cognitive function. Maintenance of the blood-brain barrier (BBB) is essen...

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Detalles Bibliográficos
Autores principales:	Berends, Eline, van Oostenbrugge, Robert J, Foulquier, Sébastien, Schalkwijk, Casper G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594715/ https://www.ncbi.nlm.nih.gov/pubmed/37875994 http://dx.doi.org/10.1186/s12987-023-00477-6

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