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An intracellular, non-oxidative factor activates in vitro chromatin fragmentation in pig sperm

BACKGROUND: In vitro incubation of epididymal and vas deferens sperm with Mn(2+) induces Sperm Chromatin Fragmentation (SCF), a mechanism that causes double-stranded breaks in toroid-linker regions (TLRs). Whether this mechanism, thought to require the participation of topoisomerases and/or DNAses a...

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Detalles Bibliográficos
Autores principales:	Viñolas-Vergés, Estel, Yeste, Marc, Garriga, Ferran, Bonet, Sergi, Mateo-Otero, Yentel, Ribas-Maynou, Jordi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594720/ https://www.ncbi.nlm.nih.gov/pubmed/37876007 http://dx.doi.org/10.1186/s40659-023-00467-w

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