Genetic Risk Assessment of Degenerative Eye Disease (GRADE): study protocol of a prospective assessment of polygenic risk scores to predict diagnosis of glaucoma and age-related macular degeneration

BACKGROUND: Glaucoma and age-related macular degeneration (AMD) account for a substantial portion of global blindness. Both conditions are highly heritable, with recognised monogenic and polygenic inheritance patterns. Current screening guidelines lack decisive recommendations. Polygenic risk scores...

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Detalles Bibliográficos
Autores principales: Hollitt, Georgina L, Qassim, Ayub, Thomson, Daniel, Schmidt, Joshua M, Nguyen, Thi Thi, Landers, John, MacGregor, Stuart, Siggs, Owen M, Souzeau, Emmanuelle, Craig, Jamie E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594830/
https://www.ncbi.nlm.nih.gov/pubmed/37875865
http://dx.doi.org/10.1186/s12886-023-03143-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594830/
https://www.ncbi.nlm.nih.gov/pubmed/37875865
http://dx.doi.org/10.1186/s12886-023-03143-5

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