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A combined bioinformatics and experimental approach identifies RMI2 as a Wnt/β-catenin signaling target gene related to hepatocellular carcinoma

BACKGROUND: The Wnt/β-catenin signaling pathway plays an important role in embryogenesis and tumorigenesis. In human cancer, abnormal activity of Wnt/β-catenin signaling pathway induces overexpressed of downstream genes, and initiate oncogene. There are several target genes known to be key players i...

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Detalles Bibliográficos
Autores principales: Tsai, Hung-Wen, Cheng, Shu-Wen, Chen, Chou-Cheng, Chen, I-Wen, Ho, Chung-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594864/
https://www.ncbi.nlm.nih.gov/pubmed/37875822
http://dx.doi.org/10.1186/s12885-023-10655-2