Conditional Control of Universal CAR T Cells by Cleavable OFF-Switch Adaptors

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[Image: see text] As living drugs, engineered T cell therapies are revolutionizing disease treatment with their unique functional capabilities. However, they suffer from limitations of potentially unpredictable behavior, toxicities, and nontraditional pharmacokinetics. Engineering conditional contro...

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Detalles Bibliográficos
Autores principales: Kvorjak, Michael, Ruffo, Elisa, Tivon, Yaniv, So, Victor, Parikh, Avani, Deiters, Alexander, Lohmueller, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594876/
https://www.ncbi.nlm.nih.gov/pubmed/37791909
http://dx.doi.org/10.1021/acssynbio.3c00320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594876/
https://www.ncbi.nlm.nih.gov/pubmed/37791909
http://dx.doi.org/10.1021/acssynbio.3c00320

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