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Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury

BACKGROUND: It is widely acknowledged that cisplatin-induced nephrotoxicity hinders its efficacy during clinical therapy. Effective pharmaceutical interventions for cisplatin-induced acute kidney injury (Cis-AKI) are currently lacking. Prior studies have implicated the chemokine CX3CL1 in the develo...

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Detalles Bibliográficos
Autores principales: Gong, Qiming, Lai, Tengfang, Liang, Liudan, Jiang, Yan, Liu, Fahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594885/
https://www.ncbi.nlm.nih.gov/pubmed/37875838
http://dx.doi.org/10.1186/s10020-023-00733-3