Two murine models of sepsis: immunopathological differences between the sexes—possible role of TGFβ1 in female resistance to endotoxemia

Endotoxic shock (ExSh) and cecal ligature and puncture (CLP) are models that induce sepsis. In this work, we investigated early immunologic and histopathologic changes induced by ExSh or CLP models in female and male mice. Remarkable results showed that females supported twice the LD100 of LPS for m...

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Detalles Bibliográficos
Autores principales: Bojalil, Rafael, Ruíz-Hernández, Armando, Villanueva-Arias, Arturo, Amezcua-Guerra, Luis Manuel, Cásarez-Alvarado, Sergio, Hernández-Dueñas, Ana María, Rodríguez-Galicia, Verónica, Pavón, Lenin, Marquina, Brenda, Becerril-Villanueva, Enrique, Hernández-Pando, Rogelio, Márquez-Velasco, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594922/
https://www.ncbi.nlm.nih.gov/pubmed/37875957
http://dx.doi.org/10.1186/s40659-023-00469-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594922/
https://www.ncbi.nlm.nih.gov/pubmed/37875957
http://dx.doi.org/10.1186/s40659-023-00469-8

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