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Two murine models of sepsis: immunopathological differences between the sexes—possible role of TGFβ1 in female resistance to endotoxemia
Endotoxic shock (ExSh) and cecal ligature and puncture (CLP) are models that induce sepsis. In this work, we investigated early immunologic and histopathologic changes induced by ExSh or CLP models in female and male mice. Remarkable results showed that females supported twice the LD100 of LPS for m...
Autores principales: | Bojalil, Rafael, Ruíz-Hernández, Armando, Villanueva-Arias, Arturo, Amezcua-Guerra, Luis Manuel, Cásarez-Alvarado, Sergio, Hernández-Dueñas, Ana María, Rodríguez-Galicia, Verónica, Pavón, Lenin, Marquina, Brenda, Becerril-Villanueva, Enrique, Hernández-Pando, Rogelio, Márquez-Velasco, Ricardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594922/ https://www.ncbi.nlm.nih.gov/pubmed/37875957 http://dx.doi.org/10.1186/s40659-023-00469-8 |
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