ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells

BACKGROUND: In eukaryotic cells, DNA double strand breaks (DSB) are primarily repaired by canonical non-homologous end joining (c-NHEJ), homologous recombination (HR) and alternative NHEJ (alt-NHEJ). Zinc finger and SCAN domain containing 4 (ZSCAN4), sporadically expressed in 1–5% mouse embryonic st...

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Detalles Bibliográficos
Autores principales: Tsai, Li-Kuang, Peng, Min, Chang, Chia-Chun, Wen, Luan, Liu, Lin, Liang, Xiubin, Chen, Y. Eugene, Xu, Jie, Sung, Li-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594928/
https://www.ncbi.nlm.nih.gov/pubmed/37875990
http://dx.doi.org/10.1186/s13578-023-01140-1