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Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine

Neoantigens/ are tumor-specific antigens that evade central immune tolerance mechanisms in the thymus. Long-term tumor-specific cytotoxic T lymphocyte activity maintenance requires class II antigen-reactive CD4(+) T cells. We had previously shown that intranodal vaccination with class I neoantigen p...

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Detalles Bibliográficos
Autores principales: Morisaki, Shinji, Onishi, Hideya, Morisaki, Takafumi, Kubo, Makoto, Umebayashi, Masayo, Tanaka, Hiroto, Koya, Norihiro, Nakagawa, Shinichiro, Tsujimura, Kenta, Yoshimura, Sachiko, Yew, Poh Yin, Kiyotani, Kazuma, Nakamura, Yusuke, Nakamura, Masafumi, Kitazono, Takanari, Morisaki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595142/
https://www.ncbi.nlm.nih.gov/pubmed/37881436
http://dx.doi.org/10.3389/fimmu.2023.1223331