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Impact of Patient Subgroups on the Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients with Advanced Illness

PURPOSE: We evaluated the impact of baseline patient characteristics on safety and efficacy of methylnaltrexone, a peripherally acting µ-opioid receptor antagonist, in patients with advanced illness with opioid-induced constipation (OIC). PATIENTS AND METHODS: This analysis pooled data from 2 random...

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Detalles Bibliográficos
Autores principales: Mehta, Neel, Slatkin, Neal E, Israel, Robert J, Stambler, Nancy, Shah, Eric D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595216/
https://www.ncbi.nlm.nih.gov/pubmed/37881233
http://dx.doi.org/10.2147/JPR.S416307