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IL-18 serves as a main effector of CAF-derived METTL3 against immunosuppression of NSCLC via driving NF-κB pathway

Background: N6-methyladenosine (m(6)A) is the most abundant modification in eukaryotic mRNA. However, its role in non-small cell lung cancer (NSCLC) has not been completely elucidated. Objective: To explore whether methyltransferase like 3 (METTL3) in cancer associated fibroblasts (CAFs) affects the...

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Detalles Bibliográficos
Autores principales: Xu, Li, Li, Kang, Li, Jia, Xu, Fang, Liang, Shuzhi, Kong, Yi, Chen, Bolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595399/
https://www.ncbi.nlm.nih.gov/pubmed/37871286
http://dx.doi.org/10.1080/15592294.2023.2265625