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Copy Number Variation in the GSTM1 and GSTT1 Genes and the Risk of Liver Cirrhosis in Eastern Ethiopia

BACKGROUND: Polymorphisms in glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) can cause an entire gene deletion. The current methodology can accurately identify GSTM1 and GSTT1 copy number variants (CNVs), which may shed light on the true contribution of each gene copy to the cellular detoxificat...

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Detalles Bibliográficos
Autores principales: Mekuria, Abraham Nigussie, Seyoum, Tamrayehu, Alemayehu, Dawit Hailu, Abebe, Markos, Nedi, Teshome, Abula, Tefera, Gong, Yun Yun, Engidawork, Ephrem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595957/
https://www.ncbi.nlm.nih.gov/pubmed/37881645
http://dx.doi.org/10.2147/TACG.S435852