Pharmacogenetics to Personalize Dosing of Tricyclic Antidepressants in Major Depressive Disorder: A Randomized Clinical Trial (PITA study)

INTRODUCTION: Tricyclic antidepressants (TCAs) have an important role in pharmacotherapy of Major Depressive Disorder (MDD). TCA dosing is aimed at achieving a concentration in the therapeutic window. Due to inter-individual differences in activity of Cytochrome P450 (CYP) 2D6 and 2C19, (enzymes inv...

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Detalles Bibliográficos
Autores principales: Ter Hark, S., Vos, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10596683/
http://dx.doi.org/10.1192/j.eurpsy.2023.275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10596683/
http://dx.doi.org/10.1192/j.eurpsy.2023.275

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