Clinical rel mutations in Staphylococcus aureus prime pathogen expansion under nutrient stress

Persistent infection by Staphylococcus aureus has been linked to the bacterial stringent response (SR), a conserved stress response pathway regulated by the Rel protein. Rel synthesizes (p)ppGpp “alarmones” in response to amino acid starvation, which enables adaptation to stress by modulating bacter...

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Detalles Bibliográficos
Autores principales: Chen, Edwin, Shaffer, Marla G., Bilodeau, Robert E., West, Raymond E., Oberly, Patrick J., Nolin, Thomas D., Culyba, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597345/
https://www.ncbi.nlm.nih.gov/pubmed/37750686
http://dx.doi.org/10.1128/msphere.00249-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597345/
https://www.ncbi.nlm.nih.gov/pubmed/37750686
http://dx.doi.org/10.1128/msphere.00249-23

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